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Home / Primary Antibodies / Monoclonal Antibodies

CD8A Monoclonal Antibody,Purified

SKU : BHA10561278

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA927984
Categories	Primary Antibodies
Clonality	monoclonal
Description	COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development. 1. Engleman EG et al. (1981) J Exp Med 153: 193-198.2. Haynes,B et al. (1986) Leukocyte TypingII: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Paes, JR. et al. (1989). Adv. Immunol. 44,256-311.4. Bikah G. et al. (1996). Science 274:1906
Host	Mouse
Isotype	IgG1
Raised In	Mouse
Reactivity	Human
Regulatory	RUO
Relevance	COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development. 1. Engleman EG et al. (1981) J Exp Med 153: 193-198. 2. Haynes,B et al. (1986) Leukocyte TypingII: Human T lymphocytes. New York: Sprimger-Verlag; 3-30. 3. Paes, JR. et al. (1989). Adv. Immunol. 44,256-311. 4. Bikah G. et al. (1996). Science 274:1906
Species	Homo Sapiens (Human)

Buffer	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Form	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
Format	liquid
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications	ELISA, FC
Description	ELISA ; FC, FACS ; ELISA
Tested Application	ELISA,FC

Datasheet
ELISA Protocol
Flow Cytometry (FC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561278	CSB-MA927984	100ul	$258		Add to Cart

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