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Home / Primary Antibodies / Monoclonal Antibodies

CD8A Monoclonal Antibody,PE Conjugated

SKU : BHA10561276

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CUSABIO TECHONOLOGY LLC

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Mfr.No.	CSB-MA574619
Categories	Primary Antibodies
Clonality	monoclonal
Description	COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development.* Ratio of CD4 and CD8 is important for monitor of HIV infection. 1. Engleman EG et al. (1981) J Exp Med 153: 193-198.2. Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30.3. Parnes, JR. et al. (1989). Adv. Immunol. 44,256-311.4. Bikah G. et al. (1996). Science 274:1906.
Host	Mouse
Isotype	IgG1
Raised In	Mouse
Reactivity	Human
Regulatory	RUO
Relevance	COV8 reacts with the 32 kDa a chain of CD8. This molecule is expressed on the T suppressor/cytotoxic cell population (which comprises about 1/3 of the peripheral blood T lymphocytes total population) and with most of thymocytes, as well as a subset of NK cells. CD8 expresses as either a heterodimer with the CD8b chain (CD8ab) or as a homodimer (CD8aa or CD8bb). CD8 acts as a co-receptor with MHC Class I restricted TCRs in antigen recognition. CD8 function is important for positive selection of MHC Class I restricted CD8+ T cells during T cell development. * Ratio of CD4 and CD8 is important for monitor of HIV infection. 1. Engleman EG et al. (1981) J Exp Med 153: 193-198. 2. Haynes, B et al. (1986) Leukocyte Typing II: Human T lymphocytes. New York: Sprimger-Verlag; 3-30. 3. Parnes, JR. et al. (1989). Adv. Immunol. 44,256-311. 4. Bikah G. et al. (1996). Science 274:1906.
Species	Homo Sapiens (Human)

Buffer	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Form	Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
Format	liquid
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Applications

ELISA, IF, FC

Description

ELISA ; IF ; FC, FACS ; ELISA ; IF

Dilution

IF	1:100-1:200

Tested Application

ELISA,IF,FC;Recommended dilution:IF:1:100-1:200

Datasheet
ELISA Protocol
Immunofluorescence (IF) Protocol
Flow Cytometry (FC) Protocol

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SKU	Supplier No.	Size	Your price	Quantity
BHA10561276	CSB-MA574619	100ul	$258		Add to Cart

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