CD154 iFluor 488 5C8 IgG2a,k (RUO)

Mfr.No.	1068114, 1068115, 1068116
Antigen	CD154
Clonality	Monoclonal
Conjugate	iFluor^TM 488
Description	The clone 5C8, a mouse monoclonal antibody, specifically recognizes a ~30-33 kDa activation-induced human CD4+ T cells surface molecule known as CD154 or CD40 ligand (CD40L). The CD40 interacts with CD154 through T cell-B cell activating molecule, gp39, TNF cytokine related activation protein. CD154 is primarily expressed on the surface of activated CD4+ T cells but can also be expressed by platelets, mast cells, macrophages, basophils, NK cells, B cells, CD8+ T cells as well as non-hematopoietic cells including smooth muscle cells, endothelial cells, and epithelial cells. CD154 plays important roles in the pathogenesis of certain blood cancer such as the CD4+ T cells of patients with CLL fail to express surface CD154 antigen even after CD3 ligation, and proximal and distal activation events are required for the neonatal CD4+ T cells for the CD154 gene transcription to establish the normal immune system.
Host	Mouse
Immunogen Region	Human D1.1 T cell line
Isotype	IgG2a,k
Reactivity	Human

Product Manual	Datasheet MSDS

Have you used this product?

Combination SKU	Supplier No.	Size	Your price
BHA19900063-1	1068114	25 test	$110	Add to Cart
BHA19900063-2	1068115	100 test	$240	Add to Cart
BHA19900063-3	1068116	200 test	$405	Add to Cart