Anti-undefined Antibody NX2,2198R Unconjugated BHA10208267

Mfr.No.	4821-RBM8-P1ABX
Alternative Names	Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
Antigen	NKX2.2
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	20p11.22
Clonality	Monoclonal
Conjugate	Unconjugated
Description	Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Host	Rabbit
Immunogen	Human recombinant NKX2.2 protein fragment (around aa1-119) (exact sequence is proprietary)
Isotype	IgG
Positive Control	Pancreas or Ewing s sarcoma
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO

Swissprot	O95096
Gene Id	4821
Clone No	NX2, 2198R
Symbol	NKX2-2
Weight	40-50kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IF, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

Flow Cytometry	0.5-1μg/million cells
Immunofluorescence	1-2μg/ml
Immunohistology (Formalin-fixed)	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208267	4821-RBM8-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody NX2,2198R Unconjugated BHA10208267

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