Anti-undefined Antibody KLC2289R Unconjugated BHA10208240

Mfr.No.	3514-RBM13-P1ABX
Alternative Names	HCAK1 ; Ig Kappa Chain C Region ; IGKC ; Immunoglobulin KM
Categories	Primary Antibodies
Cellular Localization	Secreted, Cytoplasmic, Cell Surface
Chromosome Location	2p11.2
Clonality	Monoclonal
Description	This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Host	Rabbit
Immunogen	Recombinant full-length human Ig kappa chain
Isotype	IgG
Positive Control	293T, Raji or hPBL cells. Tonsil or Spleen
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P01601
Gene Id	3514
Clone No	KLC2289R
Symbol	IGKC
Weight	~22.5kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IHC-F

Dilution

Flow Cytometry	0.5-1μg/million cells
Immunohistology (Formalin-fixed)	0.5-1.0μg/ml for 30 min at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208240	3514-RBM13-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody KLC2289R Unconjugated BHA10208240

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