CK16 ; Cytokeratin-16 ; Focal non epidermolytic palmoplantar keratoderma (FNEPPK / NEPPK) ; K1CP ; Keratin Type I Cytoskeletal 16 ; Keratin-16 ; KRT16A
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic
Chromosome Location
17q21.2
Clonality
Monoclonal
Description
Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.
Host
Rabbit
Immunogen
Recombinant full-length human KRT16 protein
Isotype
IgG
Positive Control
HeLa cells. Tonsil, Skin. Bladder, or Cervix.
Reactivity
Human
Recombinant
TRUE
Regulatory
RUO
Species
Homo Sapiens (Human)
Swissprot
P08779
Gene Id
3868
Clone No
KRT16, 2043R
Symbol
KRT16
Weight
48kDa
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Applications
FACS, IF, WB, IHC-Ff
Description
Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-Ff
Dilution
Flow Cytometry
0.5-1μg/million cells
Immunofluorescence
1-2μg/ml
Western Blotting
0.5-1μg/ml
Immunohistology (Frozen & formalin-fixed)
0.5-1μg/ml for 30 min at RT
No Description Available.
No Description Available.
Reviews of Anti-undefined Antibody KRT16,2043R Unconjugated BHA10208179