Anti-undefined Antibody PTH,1717R Unconjugated BHA10208278

Mfr.No.	5741-RBM7-P1ABX
Alternative Names	hPTH ; Parathormone ; Parathyrin ; Parathyroid hormone 1 (PTH1) ; Parathyroid hormone (PTH)
Categories	Primary Antibodies
Cellular Localization	Secreted, Cytoplasmic
Chromosome Location	11p15.3-p15.1
Clonality	Monoclonal
Description	Epitope of this MAb maps in the N-terminus of PTH, a hormone produced by the parathyroid gland that regulates the concentration of calcium and phosphorus in extracellular fluid. This hormone elevates blood Ca2+ levels by dissolving the salts in bone and preventing their renal excretion. It is produced in the parathyroid gland as an 84 amino acid single chain polypeptide. It can also be secreted as N-terminal truncated fragments or C-terminal fragments after intracellular degradation, as in case of hypercalcemia. Defects in this gene are a cause of familial isolated hypoparathyroidism (FIH); also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
Host	Rabbit
Immunogen	Recombinant human PTH protein N-terminal fragment (exact sequence is proprietary)
Isotype	IgG
Positive Control	Human parathyroid gland carcinoma
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P01270
Gene Id	5741
Clone No	PTH, 1717R
Symbol	PTH
Weight	9kDa

Buffer	200μg/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IF, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

Flow Cytometry	0.5-1μg/million cells
Immunofluorescence	0.5-1μg/ml
Immunohistology (Formalin-fixed)	0.5-1.0μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208278	5741-RBM7-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody PTH,1717R Unconjugated BHA10208278

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