Anti-undefined Antibody TIMP1,1944R Unconjugated BHA10208299

Mfr.No.	7076-RBM4-P1ABX
Alternative Names	Clgi ; Collagenase inhibitor ; Collagenase inhibitor, Human ; EPA ; EPO ; Erythroid Potentiating Activity ; Erythroid-potentiating activity ; Fibroblast collagenase inhibitor ; FLJ90373 ; HCI ; Human Collagenase Inhibitor ; Metalloproteinase inhibitor 1 ; Metalloproteinase inhibitor 1 precursor ; TIMP 1 ; TIMP ; TIMP metallopeptidase inhibitor 1 ; TIMP-1 ; TIMP1 protein ; Tissue Inhibitor of Metalloproteinase 1 ; Tissue inhibitor of metalloproteinases 1
Antigen	TIMP1
Categories	Primary Antibodies
Cellular Localization	Secreted, Cytoplasmic
Chromosome Location	Xp11.23
Clonality	Monoclonal
Conjugate	Unconjugated
Description	TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity). PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes.
Host	Rabbit
Immunogen	Recombinant full-length human TIMP1 protein
Isotype	IgG
Positive Control	293 cell extract, or rat brain lysate. Human colon carcinoma.
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P01033
Gene Id	7076
Clone No	TIMP1, 1944R
Symbol	TIMP1
Weight	23kDa

Buffer	200μg/ml of Ab purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IF, WB, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

Flow Cytometry	0.5-1μg/million cells
Immunofluorescence	0.5-1μg/ml
Western Blotting	0.5-1.0μg/ml
Immunohistology (Formalin-fixed)	0.5-1.0μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208299	7076-RBM4-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody TIMP1,1944R Unconjugated BHA10208299

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