Anti-undefined Antibody rTHBD,1591 Unconjugated BHA10208292

Mfr.No.	7056-MSM3-P1ABX
Alternative Names	AHUS6 ; BDCA3 ; CD141 ; Fetomodulin ; Thbd ; THPH12 ; THRM ; Thrombomodulin (TM)
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Cell Surface
Chromosome Location	20p11.2
Clonality	Monoclonal
Description	It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Host	Mouse
Immunogen	Recombinant fragment of human Thrombomodulin protein (around aa 69-194) (exact sequence is proprietary)
Isotype	IgG1
Positive Control	THP1 Cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P07204
Gene Id	7056
Clone No	rTHBD, 1591
Symbol	THBD
Weight	~100kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

ELISA, FACS, IF, WB, IHC-F

Description

Order Ab without BSA, Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris buffer with1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; WB ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
Flow Cytometry	0.5-1μg/million cells
Immunofluorescence	0.5-1μg/ml
Western Blotting	0.5-1μg/ml
Immunohistology (Formalin-fixed)	1-2μg/ml for 30 minutes at RT