Anti-undefined Antibody TP63,1423R Unconjugated BHA10208276

Mfr.No.	8626-RBM3-P1ABX
Alternative Names	Amplified in squamous cell carcinoma (AIS) ; Chronic ulcerative stomatitis protein (CUSP) ; EEC3 ; Keratinocyte transcription factor KET ; LMS ; NBP ; p40 ; P51/P63 ; p53 like transcription factor ; p53-related protein p63 ; RHS ; SHFM4 ; TAp63alpha ; TP53CP ; TP53L ; TP63 ; TP73 ; TP73L ; Transformation-related protein 63 ; Trp53rp1 ; Trp6 ; 3 ; Tumor protein 63 ; Tumor protein p53-like ; tumor protein p73-like
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	3q28
Clonality	Monoclonal
Description	p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
Host	Rabbit
Immunogen	Recombinant full-length human p63 protein
Isotype	IgG
Positive Control	HEK293 cells or Prostate Carcinoma or Lung or bladder squamous cell carcinoma
Reactivity	Human, Mouse, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	Q9H3D4
Gene Id	8626
Clone No	TP63, 1423R
Symbol	TP63
Weight	63kDa

Buffer	200μg/ml of Ab purified by Protein A Column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IF, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

Flow Cytometry	0.5-1μg/million cells
Immunofluorescence	1-2μg/ml
Immunohistology (Formalin-fixed)	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10208276	8626-RBM3-P1ABX	100µg	$393.20		Add to Cart

Anti-undefined Antibody TP63,1423R Unconjugated BHA10208276

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