LHR ; BA-1 ; chondroitin sulfate proteoglycan 8 (CSPG8) ; Epican ; Extracellular Matrix Receptor III (ECM III) ; GP90 Lymphocyte Homing Adhesion Receptor ; HCAM ; HCELL ; hematopoietic cell E- and L-selectin ligand ; Heparan Sulfate Proteoglycan ; Hermes Antigen ; HAS ; HUTCH I ; Hyaluronate Receptor ; Indian blood group ; Inlu Related p80 Glycoprotein ; Ly 24 ; MDU2 ; MDU3 ; MIC4 ; MUTCH I ; Phagocytic Glycoprotein 1 (PGP-1)
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
11p13
Clonality
Monoclonal
Description
This antibody recognizes an epitope encoded by exon v3 on the variant portion of human CD44. The CD44 molecule belongs to a family of cellular adhesion molecules found on a wide range of normal and malignant cells in epithelial, mesothelial and hemopoiesis tissues. CD44 is a single gene with 20 exons, of which 10 are normally expressed to encode the basic CD44 (H-CAM) molecule. The additional 10 exons (v1 to v10) are only expressed by alternative splicing of the nuclear RNA. The expression of specific cell adhesion molecule CD44 splice variants has been reported to be associated with metastasis in certain human malignancies.
Host
Mouse
Immunogen
Recombinant fragment corresponding to the v6 domain of human CD44
Isotype
IgG1 Kappa
Positive Control
Cervix or Tongue Squamous Cell Carcinoma
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Species
Homo Sapiens (Human)
Swissprot
P16070
Gene Id
960
Clone No
2F10
Symbol
CD44
Weight
80-95kDa
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Storage
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Applications
FACS, IF
Description
Optimal dilution for a specific application should be determined., FACS ; IF
Dilution
Flow Cytometry
0.5-1μg/million cells
Immunofluorescence
0.5-1μg/ml
Reviews of Anti-undefined Antibody 2F10 Unconjugated BHA10208134