Anti-undefined Antibody rSPN,839 Unconjugated BHA10207868

Mfr.No.	6693-MSM10-P0
Alternative Names	Galactoglycoprotein, GALGP, GPL115, Leukocyte sialoglycoprotein, Leukosialin, LSN, Sialophorin, SPN
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	16p11.2
Clonality	Monoclonal
Description	It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 [Workshop IV]. Epitope of MAb Bra7G is clearly different from that of MAb rSPN/839, called "b" as opposed to "a" for rSPN/839. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Host	Mouse
Immunogen	Human full-length recombinant CD43 protein
Isotype	IgG1
Positive Control	Paracortex in a tonsil or a reactive lymph node
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO

Swissprot	P16150
Gene Id	6693
Clone No	rSPN, 839
Symbol	SPN
Weight	95, 115, or 135kDa

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200μg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IF, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

Flow Cytometry	0.5-1μg/million cells
Immunofluorescence	1-2μg/ml
Immunohistology (Formalin-fixed)	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10207868	6693-MSM10-P0	20µg	$204.67		Add to Cart
BHA10207868	6693-MSM10-P0	100µg	$393.20		Add to Cart

Anti-undefined Antibody rSPN,839 Unconjugated BHA10207868

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