Anti-undefined Antibody CNN1,1408R Unconjugated BHA10207833

Mfr.No.	1264-RBM4-P0
Alternative Names	Calponin 1 basic smooth muscle ; Calponin H1 smooth muscle ; Calponin-1 ; CNN1 ; Cnn1 ; Sm Calp ; SMCC
Antigen	Calponin-1
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	19p13.2
Clonality	Monoclonal
Conjugate	Unconjugated
Description	Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Host	Rabbit
Immunogen	Recombinant full-length human CNN1 protein
Isotype	IgG
Positive Control	Myoepithelial cells in breast ducts
Reactivity	Human, Rat
Recombinant	TRUE
Regulatory	RUO
Species	Homo Sapiens (Human)

Swissprot	P51911
Gene Id	1264
Clone No	CNN1, 1408R
Symbol	CNN1
Weight	34kDa

Buffer	200μg/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200μg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml
Storage	Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Applications

FACS, IF, IHC-F

Description

Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 7.5-8.5, for 10-20 min followed by cooling at RT for 20 minutes,Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution