Anti-CD79a Antibody BHA10206933

Mfr.No.	973-RBP9-P0
Alternative Names	B lymphocyte-specific MB1 protein ; B-cell antigen receptor complex-associated protein alpha chain ; CD79a molecule immunoglobulin associated alpha ; Ig-alpha ; IGA ; IgM-alpha ; Immunoglobulin-associated alpha ; Ly54 ; MB-1 membrane glycoprotein ; Membrane-bound immunoglobulin-associated protein
Antigen	CD79a
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	19q13.2
Clonality	Polyclonal
Conjugate	Unconjugated
Description	A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells. This complex of mb-1 and B29 polypeptides and immunoglobulin constitute the B cell Ag receptor. CD79a first appears at pre B cell stage, early in maturation, and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines. Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20). This antibody will stain many of the same lymphomas as anti-CD20, but also is more likely to stain B-lymphoblastic lymphoma/leukemia than is anti-CD20. Anti-CD79a also stains more cases of plasma cell myeloma and occasionally some types of endothelial cells as well.
Host	Rabbit
Immunogen	A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein.
Positive Control	Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
Reactivity	Human, Mouse, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P11912
Uniprot	631567
Gene Id	973

Buffer	200μg/ml of Ab purified Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	0.25-0.5μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206933	973-RBP9-P0	20µg	$204.67		Add to Cart
BHA10206933	973-RBP9-P0	100µg	$393.20		Add to Cart

Anti-CD79a Antibody BHA10206933

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