Cdc2 ; CDC28A ; CDK1 ; CDKN1 ; CELL CYCLE CONTROLLER CDC2 ; Cell division control protein 2 homolog ; Cell division cycle 2 G1 to S and G2 to M ; Cell division protein kinase 1 ; Cyclin-dependent kinase 1 ; p34 Protein Kinase
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic, Nuclear
Chromosome Location
10q21.2
Clonality
Monoclonal
Description
Recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (cdk1) or p34cdc2 protein kinase. cdk1 / p34cdc2 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated cdk1 / p34cdc2 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
Host
Mouse
Immunogen
Purified recombinant human p34cdc2 fusion protein
Positive Control
HeLa or MCF-7 Cells or Tonsil
Reactivity
Human, Monkey, Cow, Mink
Recombinant
FALSE
Regulatory
RUO
Swissprot
P06493
Uniprot
334562
Gene Id
983
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
1-2μg/ml
IHC-F
2-4μg/ml for 30 minutes at RT
Reviews of Anti-Cdk1 / p34cdc2 Antibody BHA10206945