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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-Major Vault Protein (MVP) Antibody BHA10206967

SKU : BHA10206967

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NeoBiotechnologies, Inc.

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Mfr.No.	9961-MSM1-P1ABX
Alternative Names	Lung resistance-related protein (LRP) ; Major Vault Protein ; MVP ; VAULT1
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	16p11.2
Clonality	Monoclonal
Description	Recognizes a protein of 104kDa-110kDa, characterized as major vault protein (MVP). Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.
Host	Mouse
Immunogen	Proteins precipitated from human breast cancer MCF-7 cells
Positive Control	MCF-7/HeLa, breast tumors
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q14764
Uniprot	632177
Gene Id	9961

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206967	9961-MSM1-P1ABX	100µg	$393.20		Add to Cart

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