Adiponectin ; Adipocyte complement-related 30kDa protein (ACRP30) ; Adipocyte-specific secretory protein ; Adiponectin, C1Q and collagen domain containing (ACDC) ; ADIPOQ ; Adipose most abundant gene transcript 1 protein ; Adipose specific collagen like factor ; ADIPQTL1 ; ADPN ; APM-1
Categories
Primary Antibodies
Cellular Localization
Cell Surface, Cytoplasmic
Chromosome Location
3q27
Clonality
Monoclonal
Description
This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.
Host
Mouse
Immunogen
Recombinant human Adiponectin protein fragment
Positive Control
HeLa cells or Kidney
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
Q15848 (Human)
Uniprot
80485 (Human)
Gene Id
9370 (Human)
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
ELISA, IF, IHC-F, FACS
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; IF ; IHC-F ; FACS