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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD33 / SIGLEC3 (Myeloid Cell Surface Antigen) Antibody BHA10206512

SKU : BHA10206512

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NeoBiotechnologies, Inc.

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Mfr.No.	945-MSM1-P1ABX
Alternative Names	gp67 ; My9 ; Myeloid cell surface antigen CD33 ; p67 ; Sialic acid-binding Ig-like lectin 3 (SIGLEC3)
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	19q13.33
Clonality	Monoclonal
Description	Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Host	Mouse
Immunogen	Human AML cells
Positive Control	Human dendritic and mast cells. Human lymph nodes and tonsils.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P20138
Uniprot	83731
Gene Id	945

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, Func

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; Func

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
Func	Order Ab without BSA & Azide

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206512	945-MSM1-P1ABX	100µg	$393.20		Add to Cart

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