ASP4 ; Aspartyl protease 4 ; KAP ; Kidney derived aspartic protease like protein (Kdap) ; NAP1 ; NAPA ; Napsa ; napsin A aspartic peptidase ; Pronapsin A ; SNAPA
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic
Chromosome Location
19q13.33
Clonality
Monoclonal
Description
Napsin is a pepsin-like aspartic proteinase connected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
Host
Mouse
Immunogen
Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)
Positive Control
Lung adenocarcinoma
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
O96009
Uniprot
512843
Gene Id
9476
Buffer
200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA at 1.0mg/ml
Applications
FACS, IF, WB, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F