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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD37 Antibody BHA10206615

SKU : BHA10206615

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NeoBiotechnologies, Inc.

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Mfr.No.	951-MSM1-P1ABX
Alternative Names	Cell differentiation antigen 37 ; GP52 40 ; Tetraspanin-26 ; Tspan-26 ; TSPAN26
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	19q13.3
Clonality	Monoclonal
Description	Recognizes a protein of 33-55kDa, identified as CD37 (Workshop V; Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'ā€™ lymphoma (B-NHL).
Host	Mouse
Immunogen	Spleen cells of a patient with hairy cell leukemia
Positive Control	Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P11049
Uniprot	166556
Gene Id	951

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Functional Studies (Order Ab without Azide); Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206615	951-MSM1-P1ABX	100µg	$393.20		Add to Cart

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