Adipocyte membrane protein ; CHDS7 ; Collagen receptor, platelet ; fatty acid translocase (FAT) ; Fatty acid transport protein ; glycoprotein iiib (GP IIIb) ; PAS IV ; PAS-4 ; pas4 protein ; platelet collagen receptor
Categories
Primary Antibodies
Cellular Localization
Cell Surface
Chromosome Location
7q11.2
Clonality
Monoclonal
Description
Recognizes a protein of 80kDa-90kDa, identified as CD36. It is expressed on platelets, monocytes and macrophages, microvascular endothelial cells, erythrocyte precursors, mammary epithelial cells, and some macrophage derived dendritic cells. CD36 acts as a receptor for thrombospondin (TSP), collagen types I, IV and V, P. falciparum malaria-infected erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low-density lipoprotein (LDL) and recognition of apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischemia observed in sickle cell disease and cerebral malaria. Note that 1-4% of Japanese and East Asia population lack CD36.
Host
Mouse
Immunogen
Human CD36 from platelets
Positive Control
HEL or U937 cells. Platelets, monocytes, macrophages, microvascular endothelial cells in a tonsil.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P16671
Uniprot
120949
Gene Id
948
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF
Description
Functional Studies (Order Ab without Azide); Optimal dilution for a specific application should be determined., FACS ; IF