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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-CD80 (B7-1) Antibody BHA10206438

SKU : BHA10206438

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NeoBiotechnologies, Inc.

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Mfr.No.	941-MSM1-P1ABX
Alternative Names	Activation B7-1 antigen ; B lymphocyte activation antigen B7 ; B7 ; B7-1 ; BB1 ; CD28 antigen ligand 1 ; CD28LG ; CD28LG1 ; CD80 ; Costimulatory factor CD80
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	3q13.3-q21
Clonality	Monoclonal
Description	T cell proliferation and lymphokine production are triggered by occupation of the TCR by antigen, followed by a costimulatory signal that is delivered by a ligand expressed on antigen presenting cells. The B7-related cell surface proteins CD80 (B7-1) and CD86 (B7-2) are expressed on antigen presenting cells bind the homologous T cell receptors CTLA-4 (cytotoxic T lymphocyte-associated protein-4) and CD28 and trigger costimulatory signals for optimal T cell activation. CTLA-4 shares 31% overall amino acid identity with CD28 and it has been proposed that CD28 and CTLA-4 are functionally redundant. SLAM is a novel receptor on T cells that, when engaged, potentiates T cell expansion in a CD28-independent manner. B7, also designated BB1, is another ligand or counter receptor for CD28 and CTLA-4 that is expressed on the antigen-presenting cell.
Host	Mouse
Immunogen	Recombinant human full-length CD80 protein
Positive Control	Raji or Ramos Cells. Tonsil, Spleen or Thymus
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P33681
Uniprot	838
Gene Id	941

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, IF, FACS

Description

Optimal dilution for a specific application should be determined., ELISA ; IF ; FACS

Dilution

ELISA	For coating, order Ab without BSA
IF	1-2μg/ml
FACS	0.5-1μg/million cells

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206438	941-MSM1-P1ABX	100µg	$393.20		Add to Cart

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