Anti-CD47 / IAP (Integrin Associated Protein) Antibody BHA10206696

Mfr.No.	961-MSM1-P1ABX
Alternative Names	Antigenic Surface Determinant Protein OA3 ; IAP ; Integrin Associated Protein ; Integrin Associated Signal Transducer ; MER6 ; OA3 ; Protein MER6 ; Rh Related Antigen
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	3q13.12
Clonality	Monoclonal
Description	This antibody reacts with Ig domain of CD47 protein. It has been shown to inhibit polymorphonuclear neutrophil (PMN) transmigration across cell monolayers and matrix. CD47, originally named integrin-associated protein (IAP), is a 50kDa protein containing five membrane-spanning sequences and a short cytoplasmic tail. CD47 plays a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins. It is important in memory formation and synaptic plasticity in the hippocampus.Ā CD47 may play a role in membrane transport and/or integrin dependent signal transduction.Ā
Host	Mouse
Immunogen	Intact CD47 purified from placenta
Positive Control	HUVEC, OVCA3 cells, Placenta, Brain and Ovarian Tumors
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q08722
Uniprot	446414
Gene Id	961

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

Functional Studies (Order Ab without Azide); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206696	961-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-CD47 / IAP (Integrin Associated Protein) Antibody BHA10206696

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