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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-CD8A Antibody BHA10206285

SKU : BHA10206285

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NeoBiotechnologies, Inc.

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Mfr.No.	925-RBP4-P1BX
Alternative Names	CD8 antigen ; alpha polypeptide (p32) ; T8/Leu-2 T-lymphocyte differentiation antigen ; Ly3 ; LYT3 ; MAL ; T-cell surface glycoprotein CD8 alpha chain
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	2p11.2
Clonality	Polyclonal
Description	CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 β chain (CD8 α/β) or as a homodimer (CD8 α/α). A majority of thymocytes and a subpopulation of mature T cells and NK cell express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4+/CD8-. Anaplastic large cell lymphoma is usually CD4+ and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.
Host	Rabbit
Immunogen	Human CD8 recombinant fragment corresponding to aa 200-250
Positive Control	HuT78 or hPBL. Tonsil
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P01732
Uniprot	85258
Gene Id	925

Buffer	200g/ml of antibody purified from rabbit anti-serum by Protein A chromatography. Supplied in 10mM PBS, pH 7.4 with 0.05% BSA and 0.05% sodium azide. Contact us if you require this antibody in a different format.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	1-2μg/million cells in 0.1ml
IF	1-2μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206285	925-RBP4-P1BX	100µg	$393.20		Add to Cart

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