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Home / Primary Antibodies / Monoclonal Antibodies

Anti-CD7 Antibody BHA10206220

SKU : BHA10206220

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NeoBiotechnologies, Inc.

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Mfr.No.	924-MSM1-P1ABX
Alternative Names	GP40 ; Leu9 ; p41 ; T-cell leukemia antigen ; T-cell surface antigen Leu-9 ; Tp40 ; TP41
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	17q25.3
Clonality	Monoclonal
Description	Recognizes a protein of 40kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation.
Host	Mouse
Immunogen	Chronic Lymphoid Leukemia cells (CLL)
Positive Control	Jurkat, HUT-78, Molt-4, CEM cells, or human peripheral blood lymphocytes. Lymph node and tonsil.
Reactivity	Human, Pig, Guinea pig
Recombinant	FALSE
Regulatory	RUO

Swissprot	P09564
Uniprot	186820
Gene Id	924

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206220	924-MSM1-P1ABX	100µg	$393.20		Add to Cart

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