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Home / Primary Antibodies / Monoclonal Antibodies

Anti-Aurora B Antibody BHA10206186

SKU : BHA10206186

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NeoBiotechnologies, Inc.

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Mfr.No.	9212-MSM1-P1ABX
Alternative Names	AIK2 ; AIM-1 ; ARK-2 ; AurB ; AURKB ; Aurora-1 ; Aurora and Ipl1 like midbody associated protein 1 ; Aurora kinase B ; Aurora-B ; Aurora-related kinase 2
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Nuclear
Chromosome Location	17p13.1
Clonality	Monoclonal
Description	Recognizes a protein of 39kDa, which is identified as Aurora B. The serine/threonine protein kinase aurora B (Aurora B) is a chromosomal passenger protein critical for accurate chromosome segregation, cytokinesis, protein localization to the centromere and kinetochore, correct microtubule-kinetochore attachment, and regulation of the mitotic checkpoint. Aurora B forms a tight complex with inner centrosome protein and survivin. Inactivation of any of these proteins causes similar defects in chromosome segregation. A significant overexpression of Aurora B has been found in a variety of human tumors including non-small cell lung carcinoma, astrocytoma, seminoma and carcinomas of the colon, prostate, endometrium and thyroid. The expression level of Aurora B is associated with cell proliferation and prognosis in these tumors.
Host	Mouse
Immunogen	Recombinant human Aurora B protein fragment (aa89-251) (exact sequence is proprietary)
Positive Control	HeLa cells. Tonsil, Placenta, Hodgkin s Lymphoma or Colon Carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q96GD4
Uniprot	442658
Gene Id	9212

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206186	9212-MSM1-P1ABX	100µg	$393.20		Add to Cart

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