Anti-CD5 Antibody BHA10206170

Mfr.No.	921-MSM3-P1ABX
Alternative Names	CD5 antigen (p56 62) ; LEU1 ; Ly12 ; LyA ; Lymphocyte antigen T1/Leu-1 ; Lymphocyte glycoprotein T1/Leu1 ; T-cell surface glycoprotein CD5
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	11q12.2
Clonality	Monoclonal
Description	Recognizes a 67kDa transmembrane protein, which is identified as CD5. The CD5 antigen is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. Anti-CD5 is a pan T-cell marker that also reacts with a range of neoplastic B-cells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10%) of diffuse large B-cell lymphoma. CD5 aberrant expression is useful in making a diagnosis of mature T-cell neoplasms. Anti-CD5 detection is diagnostic in CLL/SLL within a panel of other B-cell markers, especially one that includes anti-CD23. Anti-CD5 is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, anti-CD5 can be used in distinguishing thymic carcinoma (+) from thymoma (-). Anti-CD5 does not react with granulocytes or monocytes.
Host	Mouse
Immunogen	Human CD5 recombinant protein (C5/473); A synthetic peptide from the intracellular region of human CD5 (CD5/54/F6)
Positive Control	293T, Ramos, or MOLT-4 Cells. Tonsil.
Reactivity	Human, Rabbit, Cow, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P06127
Uniprot	58685
Gene Id	921

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10206170	921-MSM3-P1ABX	100µg	$393.20		Add to Cart

Anti-CD5 Antibody BHA10206170

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