Anti-p40 (deltaNp63) Antibody BHA10205970

Mfr.No.	8626-RBP1-P1ABX
Alternative Names	deltaNp63, TP63
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	3q28
Clonality	Polyclonal
Description	p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibodyā€™s ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques.
Host	Rabbit
Immunogen	A synthetic peptide (ENNAQTQFSEPQY) corresponding to aa5-17 of human p40
Positive Control	HEK293 cells or Prostate Carcinoma or Lung Squamous Cell Carcinoma
Reactivity	Human, Mouse, Rat, Cow
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9H3D4
Uniprot	137569
Gene Id	8626

Buffer	200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205970	8626-RBP1-P1ABX	100µg	$393.20		Add to Cart

Anti-p40 (deltaNp63) Antibody BHA10205970

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