CD 3E ; CD3 epsilon ; CD3 TCR complex ; CD3E ; CD3e antigen epsilon polypeptide (TiT3 complex) ; T cell antigen receptor complex epsilon subunit of T3 ; T-cell surface antigen T3/Leu-4 epsilon chain ; T-cell surface glycoprotein CD3 epsilon chain ; T3E ; TCRE
Antigen
CD3e
Categories
Primary Antibodies
Cellular Localization
Cell Surface, Cytoplasmic
Chromosome Location
11q23.3
Clonality
Polyclonal
Description
Recognizes the -chain of CD3, which consists of five different polypeptide chains (designated as γ, δ, ε, ζ, and η) with MW ranging from 16-28kDa. The CD3 complex is closely associated at the lymphocyte cell surface with the T cell antigen receptor (TCR). Reportedly, CD3 complex is involved in signal transduction to the T cell interior following antigen recognition. The CD3 antigen is first detectable in early thymocytes and probably represents one of the earliest signs of commitment to the T cell lineage. In cortical thymocytes, CD3 is predominantly intra-cytoplasmic. However, in medullary thymocytes, it appears on the T cell surface. CD3 antigen is a highly specific marker for T cells, and is present in majority of T cell neoplasms.
Host
Rabbit
Immunogen
A synthetic peptide aa156-168 (ERPPPVPNPDYEP) from human CD3e
200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA at 1.0mg/ml
Applications
FACS, IF
Description
Optimal dilution for a specific application should be determined., FACS ; IF