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Home / Primary Antibodies / Monoclonal Antibodies

Anti-p63 Antibody BHA10205964

SKU : BHA10205964

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NeoBiotechnologies, Inc.

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Mfr.No.	8626-MSM6-P1ABX
Alternative Names	Amplified in squamous cell carcinoma (AIS) ; Chronic ulcerative stomatitis protein (CUSP) ; EEC3 ; Keratinocyte transcription factor KET ; LMS ; NBP ; p40 ; P51/P63 ; p53 like transcription factor ; p53-related protein p63
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	3q28
Clonality	Monoclonal
Description	p63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S). p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.
Host	Mouse
Immunogen	Recombinant human p63 protein fragment (aa3-106) (exact sequence is proprietary)
Positive Control	HEK293 cells or Prostate Carcinoma or Lung or bladder squamous cell carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9H3D4
Uniprot	137569
Gene Id	8626

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205964	8626-MSM6-P1ABX	100µg	$393.20		Add to Cart

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