Anti-VLDL-Receptor (Very Low Density Lipoprotein Receptor) Antibody BHA10205762

Mfr.No.	7436-MSM1-P1ABX
Alternative Names	Very low-density lipoprotein receptor ; VLDL receptor ; VLDL-R ; VLDLR
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	9p24
Clonality	Monoclonal
Description	VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
Host	Mouse
Immunogen	Recombinant human VLDLR fragment from c-terminal (exact sequence is proprietary)
Positive Control	HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.
Reactivity	Human, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P98155 (Human)
Uniprot	370422 (Human)
Gene Id	7436 (Human)

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
WB	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205762	7436-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-VLDL-Receptor (Very Low Density Lipoprotein Receptor) Antibody BHA10205762

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