Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
Host
Rabbit
Immunogen
A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
Positive Control
HEK293 cells or bladder carcinoma
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
O75631
Uniprot
632787
Gene Id
7380
Buffer
200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA at 1.0mg/ml
Applications
FACS, IF, WB
Description
Optimal dilution for a specific application should be determined., FACS ; IF ; WB