Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Antibody BHA10205322

Mfr.No.	7077-MSM1X-P1ABX
Alternative Names	Metalloproteinase inhibitor 2 ; TIMP metallopeptidase inhibitor 2 ; TIMP-2 ; TIMP2 ; Tissue Inhibitor of Metalloproteinase 2
Antigen	TIMP2 (Tissue Inhibitor of Metalloproteinase 2)
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	17q25
Clonality	Monoclonal
Conjugate	Unconjugated
Description	It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Host	Mouse
Immunogen	A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)
Isotype	IgG2a Kappa
Positive Control	HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.
Reactivity	Human, Mouse, Rat, Guinea pig, Rabbit, Cow, Zebrafish
Recombinant	FALSE
Regulatory	RUO

Swissprot	P16035
Uniprot	633514
Gene Id	7077

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
WB	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205322	7077-MSM1X-P1ABX	100µg	$393.20		Add to Cart

Anti-TIMP2 (Tissue Inhibitor of Metalloproteinase 2) Antibody BHA10205322

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