Anti-CD43 Antibody BHA10205061

Mfr.No.	6693-MSM4-P1ABX
Alternative Names	Galactoglycoprotein ; GALGP ; GPL115 ; Leukocyte sialoglycoprotein ; Leukosialin ; LSN ; Sialophorin ; SPN
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	16p11.2
Clonality	Monoclonal
Description	It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43 (Workshop V). Epitope of MAb Bra7G is clearly different from that of MAb DF-T1, called b as opposed to a for DF-T1. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Host	Mouse
Immunogen	Immature pluripotent human leukemia K562 cells
Isotype	IgM Kappa
Positive Control	Paracortex in a tonsil or a reactive lymph node
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P16150
Uniprot	632188
Gene Id	6693

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by PEG precipitation. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues, digest sections with trypsin at 1mg/ml PBS, 15 min at room temp); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205061	6693-MSM4-P1ABX	100µg	$393.20		Add to Cart

Anti-CD43 Antibody BHA10205061

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