Anti-Thrombomodulin / CD141 Antibody BHA10205297

Mfr.No.	7056-MSM2-P1ABX
Alternative Names	AHUS6 ; BDCA3 ; CD141 ; Fetomodulin ; Thbd ; THPH12 ; THRM ; Thrombomodulin (TM)
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	20p11.2
Clonality	Monoclonal
Description	It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.
Host	Mouse
Immunogen	Recombinant human Thrombomodulin protein fragment (aa69-194) (exact sequence is proprietary)
Isotype	IgG2a Kappa
Positive Control	THP1 Cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P07204
Uniprot	2030
Gene Id	7056

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris buffer with1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., ELISA ; FACS ; IF ; IHC-F

Dilution

ELISA	Use Ab at 2-4μg/ml for coating
FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205297	7056-MSM2-P1ABX	100µg	$393.20		Add to Cart

Anti-Thrombomodulin / CD141 Antibody BHA10205297

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