Anti-CD147 / EMMPRIN / Neurothelin Antibody BHA10205108

Mfr.No.	682-MSM1-P1ABX
Alternative Names	5A11 Antigen ; 5F7 ; Basigin ; Blood brain barrier HT7 antigen BSG ; Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) ; Leukocyte Activation Antigen M6 ; Neurothelin ; OK Blood Group Antigen ; TCSF ; Tumor Cell-derived Collagenase Stimulatory Factor
Antigen	CD147 / EMMPRIN / Neurothelin
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	19p13.3
Clonality	Monoclonal
Conjugate	Unconjugated
Description	This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
Host	Mouse
Immunogen	Human T cell line Molt 13
Isotype	IgG1
Positive Control	HSB2 cells. Renal Cell, Ovarian carcinoma or Melanoma
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P35613
Uniprot	501293
Gene Id	682

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

Inhibits Homotypic Aggregation, Adhesion to Matrix Proteins, and Migation through Matrigel (Order Ab without BSA/Azide); (Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1:100-1:200
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10205108	682-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-CD147 / EMMPRIN / Neurothelin Antibody BHA10205108

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