Anti-gp100 / Melanosome / PMEL17 / SILV Antibody BHA10204941

Mfr.No.	6490-RBM5-P1ABX
Alternative Names	95kDa melanocyte-specific secreted glycoprotein ; M-beta ; Melanocyte lineage specific antigen GP100 ; Melanocyte protein Pmel 17 ; Melanoma associated ME20 antigen ; Melanosomal matrix protein17 ; p100 ; p26 ; PMEL17 ; Premelanosome protein
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	12q13.2
Clonality	Monoclonal
Description	Cytotoxic T lymphocytes (CTL s) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.
Host	Rabbit
Immunogen	Recombinant full-length human SILV protein
Isotype	IgG Kappa
Positive Control	SK-MEL-28 cells or Melanoma
Reactivity	Human
Recombinant	TRUE
Regulatory	RUO

Swissprot	P40967
Uniprot	95972
Gene Id	6490

Buffer	200μg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	0.5-1.0μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204941	6490-RBM5-P1ABX	100µg	$393.20		Add to Cart

Anti-gp100 / Melanosome / PMEL17 / SILV Antibody BHA10204941

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