Anti-S100A9 Antibody BHA10204839

Mfr.No.	6280-MSM6-P1ABX
Alternative Names	S100-A9 ; MRP14 ; calgranulin-B ; calprotectin L1H subunit ; leukocyte L1 complex heavy chain ; migration inhibitory factor-related protein 14 ; S100 calcium-binding protein A9 (calgranulin B)Human Gene SymbolS100A9Hu Gene Location1q21
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Extracellular(secreted), Cell Surface
Chromosome Location	1q21
Clonality	Monoclonal
Description	This MAb stains the cytoplasm of macrophages and histiocytes in hematopoietic organs, Kupfferā€™s cells of the liver and Langerhanā€™s cells of the skin. It also stains the mantle zone B-lymphocytes of the lymph node and spleen, spermatogonia, and chief cells of the stomach. S100A9 is expressed by macrophages in acutely inflamed tissues and in chronic inflammation. It is detected in peripheral blood leukocytes, in neutrophils and granulocytes. It is present at sites of vascular inflammation. S100A9 is also expressed in epithelial cells constitutively or induced during dermatoses. S100A9 is a Calcium-binding protein. It has antimicrobial activity towards bacteria and fungi. It is important for resistance to invasion by pathogenic bacteria. It up-regulates transcription of genes that are under the control of NF-kappa-B. S100A9 plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS). It promotes tubulin polymerization when unphosphorylated. It also promotes phagocyte migration and infiltration of granulocytes at sites of wounding. It plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1.
Host	Mouse
Immunogen	Human peripheral blood monocyte components
Isotype	IgG1 Kappa
Positive Control	Liver or histiocytoma
Reactivity	Human, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P06702
Uniprot	112405
Gene Id	6280

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% azide. Also available WITHOUT azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

Staining of formalin-fixed, paraffin-embedded tissues, digest with trypsin at 1mg/ml PBS, 15 min at RT Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204839	6280-MSM6-P1ABX	100µg	$393.20		Add to Cart

Anti-S100A9 Antibody BHA10204839

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