S100A4 ; S100 calcium-binding protein A4 ; Calvasculin ; CAPL ; Fibroblast specific protein 1 (FSP1) ; Leukemia multidrug resistance associated protein ; Malignant transformation suppression 1 (MTS1) ; Metastasin ; Placental calcium-binding protein
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic, Nuclear
Chromosome Location
1q21
Clonality
Monoclonal
Description
S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, α6β4 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
Host
Mouse
Immunogen
Recombinant human S100A4 protein
Isotype
IgG1 Kappa
Positive Control
HeLa, A549 or A375 Cells. Placenta
Reactivity
Human, Mouse
Recombinant
FALSE
Regulatory
RUO
Swissprot
P26447
Uniprot
654444
Gene Id
6275
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, WB, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F