Anti-Bax Antibody BHA10204594

Mfr.No.	581-MSM1-P1ABX
Alternative Names	Apoptosis regulator BAX cytoplasmic isoform beta ; Apoptosis regulator BAX membrane isoform alpha ; Bax isoform psi ; Bax protein cytoplasmic isoform delta ; Bax protein cytoplasmic isoform gamma ; Bax zeta ; Bcl-2-like protein 4 ; BCL2 associated X protein ; BCL2 associated X protein omega ; BCL2 associated X protein transcript variant delta2
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	19q13.33
Clonality	Monoclonal
Description	Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.
Host	Mouse
Immunogen	A synthetic peptide, aa 3-16 (Cys-GSGEQPRGGGPTSS) of human bax protein.
Isotype	IgG1
Positive Control	Jurkat, K562, HL-60, or HeLa Cells. Reed-Sternberg cells in Hodgkin s lymphoma.
Reactivity	Human, Monkey
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q07812
Uniprot	624291
Gene Id	581

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	1-2μg/ml
WB	0.5-1μg/ml
IHC-F	0.5-1μg/ml for 30 minutes at RT

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204594	581-MSM1-P1ABX	100µg	$393.20		Add to Cart

Anti-Bax Antibody BHA10204594

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