Androgen binding protein (ABP) ; Sex hormone-binding globulin (SHBG) ; Sex steroid binding protein (SBP) ; Sex steroid-binding protein ; Testis-specific androgen-binding protein ; Testosterone binding beta globulin ; Testosterone-Estradiol-Binding Globulin (TEBG)
Categories
Primary Antibodies
Cellular Localization
Cytoplasmic, Extracellular(secreted)
Chromosome Location
17p13.1
Clonality
Monoclonal
Description
Recognizes a protein of 45kDa, identified as SHBG. It functions as an androgen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule and transported to the epididymis.
Host
Mouse
Immunogen
Recombinant full-length human SHBG protein
Isotype
IgG1
Positive Control
Liver, Placenta or Testis
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P04278
Uniprot
632235
Gene Id
6462
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF, IHC-F
Description
(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
IHC-F
1-2μg/ml for 30 minutes at RT
Reviews of Anti-Sex Hormone Binding Globulin (SHBG) Antibody BHA10204897