Anti-CD162 (Selectin P Ligand) Antibody BHA10204885

Mfr.No.	6404-MSM2-P1ABX
Alternative Names	CD162 ; CLA ; Cutaneous lymphocyte associated antigen ; P-selectin glycoprotein ligand 1 ; PSGL1 ; Selectin P ligand ; SELPLG
Categories	Primary Antibodies
Cellular Localization	Cell Surface
Chromosome Location	12q24
Clonality	Monoclonal
Description	CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.
Host	Mouse
Immunogen	Recombinant human full-length SELPLG (CD162) protein
Isotype	IgG1
Positive Control	Jurkat cells. Tonsil or Spleen
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q14242
Uniprot	591014
Gene Id	6404

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10mM Tris with 1mM EDTA, pH 9.0 for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution

FACS	0.5-1μg/million cells
IF	0.5-1μg/ml
IHC-F	1-2μg/ml for 30 minutes at RT

No Description Available.

Have you used this product?

Rate it now..!!

SKU	Supplier No.	Size	Your price	Quantity
BHA10204885	6404-MSM2-P1ABX	100µg	$393.20		Add to Cart

Anti-CD162 (Selectin P Ligand) Antibody BHA10204885

Contact us to order

Tel

Email

Contact us to order

Tel

Email

Reviews of Anti-CD162 (Selectin P Ligand) Antibody BHA10204885

Rate it now..!!