B2M ; Beta 2 microglobin ; Beta 2 microglobulin ; Beta chain of MHC class I molecules ; Beta-2-microglobulin form pI 5.3 ; Hdcma22p
Categories
Primary Antibodies
Cellular Localization
Cell Surface, Extracellular(secreted)
Chromosome Location
15q21-q22.2
Clonality
Monoclonal
Description
Recognizes a protein of 12kDa, identified as ļ� �ļ€ �ļ€ �microglobulin. Beta-ļ€ �-microglobulin non-covalently associates with the 44kDa ļ�� chain to form the HLA Class I antigen complex. Humanļ€ļ� �eta-ļ€ �-microglobulin associated with HLA Class I antigens is expressed on many types of cells including lymphocytes, thymocytes, monocytes, granulocytes, platelets, endothelial cells, and epithelial cells. It is absent on erythrocytes. This MAb is specific to humanļ€ļ� �ļ€ �-microglobulin and does not react with non-human primate cells. This antibody reacts with all cell types excluding erythrocytes. The detection of Ć�2Āmicroglobulin in body fluids has been used as a tumor marker and for monitoring patients with HIV infection.
Host
Mouse
Immunogen
Human PBL s from a T-cell acute lymphoblastic leukemia (T-ALL) patient
Isotype
IgG2a Kappa
Positive Control
HL-60 or HeLa cells. Melanomas and Lymphoma. Carcinoma of Stomach, Cervix, Endometrial, Kidney or Colon.
Reactivity
Human
Recombinant
FALSE
Regulatory
RUO
Swissprot
P61769
Uniprot
534255
Gene Id
567
Buffer
200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration
1.0mg/ml
Description
There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity
Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Applications
FACS, IF
Description
Optimal dilution for a specific application should be determined., FACS ; IF
Dilution
FACS
0.5-1μg/million cells in 0.1ml
IF
0.5-1μg/ml
Reviews of Anti-Beta-2 Microglobulin Antibody BHA10204349