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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-UACA / Nucling Antibody BHA10204265

SKU : BHA10204265

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NeoBiotechnologies, Inc.

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Mfr.No.	55075-MSM2-P1ABX
Alternative Names	Nuclear membrane binding protein ; Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) ; NUCLING
Categories	Primary Antibodies
Cellular Localization	Nuclear membrane
Chromosome Location	15q22-q24
Clonality	Monoclonal
Description	UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.
Host	Mouse
Immunogen	Recombinant human UACA protein
Isotype	IgG1 Kappa
Positive Control	HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
Reactivity	Human, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9BZF9
Uniprot	108049
Gene Id	55075

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1.0μg/ml
WB	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204265	55075-MSM2-P1ABX	100µg	$393.20		Add to Cart

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