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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-PTEN (Tumor Suppressor Protein) Antibody BHA10204382

SKU : BHA10204382

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NeoBiotechnologies, Inc.

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Mfr.No.	5728-RBP1-P1ABX
Alternative Names	Bannayan Zonana syndrome (BZS) ; DEC ; GLM2 ; ITGA 2 ; MHAM ; Multiple hamartoma (Cowden syndrome) ; Mutated in Mutiple Advanced Cancers 1 (MMAC1) ; Phosphatase and tensin like protein ; Phosphatidylinositol 345 trisphosphate 3 phosphatase ; Platelet antigen BR
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Nuclear
Chromosome Location	10q23.3
Clonality	Polyclonal
Description	Recognizes a protein of 55kDa, which is identified as PTEN. PTEN is one of the most commonly lost tumor suppressors in human cancer; in fact, up to 70% of men with prostate cancer are estimated to have lost a copy of the PTEN gene at the time of diagnosis. During tumor development, mutations and deletions of PTEN occur that inactivate its enzymatic activity leading to increased cell proliferation and reduced cell death. Frequent genetic inactivation of PTEN occurs in glioblastoma, endometrial cancer, and prostate cancer; and reduced expression is found in many other tumor types such as lung and breast cancer. In breast and prostate cancer, loss of PTEN expression has been shown to correlate positively with advanced stage. Furthermore, PTEN mutation also causes a variety of inherited predispositions to cancer.
Host	Rabbit
Immunogen	Recombinant full-length human PTEN protein
Isotype	Ig
Positive Control	HeLa cells. Prostate Carcinoma.
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	P60484
Uniprot	500466
Gene Id	5728

Buffer	200μg/ml of Ab purified from rabbit anti-serum by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells
IF	1-2μg/ml
WB	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10204382	5728-RBP1-P1ABX	100µg	$393.20		Add to Cart

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