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Home / Primary Antibodies / Monoclonal Antibodies

Anti-PAX6 Antibody BHA10203910

SKU : BHA10203910

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NeoBiotechnologies, Inc.

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Mfr.No.	5080-MSM1-P1ABX
Alternative Names	AN2 ; Aniridia type II protein ; Oculorhombin ; Paired box gene 6 (aniridia keratitis) ; Paired box homeotic gene 6 ; Paired box protein Pax-6 ; Sey ; WAGR
Categories	Primary Antibodies
Cellular Localization	Nuclear
Chromosome Location	11p13
Clonality	Monoclonal
Description	Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Host	Mouse
Immunogen	Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein
Isotype	IgG1 Kappa
Positive Control	Pancreas or Cerebellum
Reactivity	Human, Mouse, Rat, Chicken
Recombinant	FALSE
Regulatory	RUO

Swissprot	P26367
Uniprot	611376
Gene Id	5080

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, WB

Description

Optimal dilution for a specific application should be determined., FACS ; IF ; WB

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml
WB	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203910	5080-MSM1-P1ABX	100µg	$393.20		Add to Cart

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