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Home / Primary Antibodies / Monoclonal Antibodies

Anti-NOX4 / NADPH Oxidase 4 Antibody BHA10203904

SKU : BHA10203904

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NeoBiotechnologies, Inc.

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Mfr.No.	50507-MSM1-P1ABX
Alternative Names	Kidney oxidase-1 ; Kidney superoxide-producing NADPH oxidase ; KOX-1 ; NADPH oxidase 4 ; Nox4 ; Renal NAD(P)H-oxidase ; RENOX
Categories	Primary Antibodies
Cellular Localization	Cell Surface, Cytoplasmic
Chromosome Location	11q14.2-q21
Clonality	Monoclonal
Description	The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. The p22 and gp91-phox subunits also function as surface O2 sensors that initiate cellular signaling in response to hypoxic conditions. NOX4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. It is also expressed in fetal tissues, placenta, glioblastoma and vascular cells.
Host	Mouse
Immunogen	Recombinant human NOX4 protein
Isotype	IgG2b Kappa
Positive Control	PC-12, JAR cells. Kidney
Reactivity	Human
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9NPH5
Uniprot	371036
Gene Id	50507

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

ELISA, IF, WB, FACS

Description

Optimal dilution for a specific application should be determined., ELISA ; IF ; WB ; FACS

Dilution

ELISA	For coating, order Ab without BSA
IF	0.5-1μg/ml
WB	0.5-1μg/ml
FACS	0.5-1μg/million cells

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203904	50507-MSM1-P1ABX	100µg	$393.20		Add to Cart

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