Anti-Ornithine Decarboxylase-1 (ODC-1) Antibody BHA10203879

Mfr.No.	4953-MSM1-P0
Alternative Names	Ornithine decarboxylase structural 1 ; RNODC
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	2p25.1
Clonality	Monoclonal
Description	Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.
Host	Mouse
Immunogen	Recombinant human ODC-1 protein
Isotype	IgG1 Kappa
Positive Control	PC3 cells. Placenta, Prostate or Testicular carcinoma.
Reactivity	Human, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P11926
Uniprot	467701
Gene Id	4953

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	200µg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab with BSA and Azide at 200μg/ml

Applications

FACS, IF, WB, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; WB ; IHC-F

Dilution