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Home / Primary Antibodies / Flow Cytometry (FACS)

Anti-FOXP3 (Forkhead Box Protein P3) / Scurfin Antibody BHA10203942

SKU : BHA10203942

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NeoBiotechnologies, Inc.

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Mfr.No.	50943-MSM1-P1ABX
Alternative Names	JM2 ; AIID ; DIETER ; IPEX ; MGC141961 ; MGC141963 ; PIDX ; XPID ; FOXP3delta7 ; forkhead box protein P3
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic, Nuclear
Chromosome Location	Xp11.23
Clonality	Monoclonal
Description	Recognizes a protein of 47-55kDa, which is identified as FOXP3. Its precise epitope is not known, but it has been mapped to the N-terminal portion (amino acids 2-136) of the protein.The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. During early development, FOXP1 and FOXP2 are expressed abundantly in the lung, with lower levels of expression in neural, intestinal and cardiovascular tissues, where they act as transcription repressors. FOXP1 is widely expressed in adult tissues, while neoplastic cells often exhibit a dramatic change in expression level or localization of FOXP1. Mutations in FOXP3 gene cause IPEX, a fatal, X-linked inherited disorder characterized by immune dysregulation. The FOXP3 protein is essential for normal immune homeostasis. Specifically, FOXP3 represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Host	Mouse
Immunogen	Full-length His-tagged mouse FOXP3 protein
Isotype	IgG1 Kappa
Positive Control	Tonsil, lymph node or Breast carcinoma
Reactivity	Human, Monkey, Mouse
Recombinant	FALSE
Regulatory	RUO

Swissprot	Q9BZS1
Uniprot	247700
Gene Id	50943

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA; 0.05% azide. Also available WITHOUT BSA; azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF

Description

Optimal dilution for a specific application should be determined., FACS ; IF

Dilution

FACS	0.5-1μg/million cells in 0.1ml
IF	0.5-1μg/ml

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SKU	Supplier No.	Size	Your price	Quantity
BHA10203942	50943-MSM1-P1ABX	100µg	$393.20		Add to Cart

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