Anti-Smooth Muscle Myosin Heavy Chain (SM-MHC) Antibody BHA10203634

Mfr.No.	4629-MSM3-P1ABX
Alternative Names	AAT4 ; Myosin heavy chain 11 (MYH11) ; Myosin heavy chain 11 smooth muscle ; Smooth muscle myosin heavy chain 11 ; Myosin-11 ; SM1 ; SM2 ; SMHC ; SMMHC
Categories	Primary Antibodies
Cellular Localization	Cytoplasmic
Chromosome Location	16p13.11
Clonality	Monoclonal
Description	Smooth muscle myosin heavy chain (SM-MHC) is a cytoplasmic structural protein, which is a major component of the contractile apparatus in smooth muscle cells. Expression of smooth muscle myosin is developmentally regulated, appearing early in smooth muscle development, and is specific for smooth muscle development. Two isoforms of smooth muscle myosin heavy chain have been identified, designated MHC-1 and MHC-2. The antibody may be useful for the study of breast tumors as the presence of an intact layer of myoepithelial cells is an important feature, which may distinguish benign breast lesions and carcinoma in situ from invasive tumors.
Host	Mouse
Immunogen	Recombinant human MYH11 protein
Isotype	IgG1 Kappa
Positive Control	Uterus or normal breast
Reactivity	Human, Rat
Recombinant	FALSE
Regulatory	RUO

Swissprot	P35749
Uniprot	460109
Gene Id	4629

Buffer	200μg/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Concentration	1.0mg/ml
Description	There are no warranties, expressed or implied, which extend beyond this description. Company is not liable for any personal injury or economic loss resulting from this product.
Purity	Purified Ab WITHOUT BSA and Azide at 1.0mg/ml

Applications

FACS, IF, IHC-F

Description

(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes); Optimal dilution for a specific application should be determined., FACS ; IF ; IHC-F

Dilution